The pronoun this (in bold type in the 2nd paragraph) refers to
a) the fact that drugs that seem promising in lab and animal studies have a notoriously high failure rate in human trials.
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b) phosphoethanolamine has been shown to kill tumor cells only in lab dishes and in mice, not humans.
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c) some chemists at the University of São Paulo’s campus in São Carlos have manufactured the compound for years.
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d) those patients who have claimed remarkable recoveries, perpetuating the compound’s reputation.
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e) administrators at the university estimate that it covers about 80% of the orders they have received for the compound.
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